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Dexamethasone is used to test the level of cortisol hormone in the body. Injection of dexamethasone will cause a decreased level of cortisol in a normal pet; however, in a pet with Cushing's disease, there is minimal or no decrease in cortisol level. Other diseases can suppress cortisol production, so it is important to rule these out prior to dexamethasone testing. Knowing the type of Cushing's disease your pet has can guide treatment decisions and offers a more defined prognosis.
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Dexmedetomidine is a sedative/tranquilizer used primarily in cats and dogs as a pre-medication injection for anesthesia or for chemical restraint. It is also used orally in dogs for short-term anxiety management. The most common side effect is a low heart rate. Dexmedetomidine should not be used in patients with severe heart liver or kidney disease. It should be used cautiously in young, old, or weak animals. Consult your veterinary office immediately if you suspect a negative reaction or overdose.
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Dextromethorphan is given by mouth and is used off label to treat compulsive behaviors and occasionally used to treat cough. Side effects are uncommon but may include vomiting, diarrhea, decreased appetite, sleepiness, drooling or anxiousness. Do not use in pets that are allergic to it.
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Dextromethorphan + Guaifenesin is given by mouth as a tablet and is used off label to reduce cough in dogs and cats or to treat compulsive behavior. Side effects are uncommon, but serious adverse reactions associated with this drug may occur without warning. Contact your veterinarian if you notice anything out of the ordinary.
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Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their cat's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.
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Testing for diabetes includes confirming hyperglycemia and glucosuria while looking for other conditions by taking a complete blood count (anemia, infection), biochemistry profile (hepatic disease, pancreatitis), and a urinalysis (urinary tract infection). Monitoring includes regular glucose curves and additional exams and testing based on the pet owner's monitoring of their dog's clinical signs at home. Urine glucose testing and fructosamine are sometimes used in diabetic monitoring and urine testing for infection may be recommended.
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Diabetes insipidus is rare in cats and is characterized by excessive drinking and the production of enormous volumes of extremely dilute urine. Despite drinking large volumes of water, the cat can become dehydrated from urinating so much. Increased drinking and urination are common signs of several other health conditions, so it is essential that several diagnostic tests be performed to diagnose diabetes insipidus. While the condition is rarely curable, it is usually successfully controlled.
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Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.
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Diabetes mellitus results from an inadequate production of insulin from the pancreas. The primary treatment is replacement by insulin injections. The body’s response to the injections needs to be regularly monitored by glucose curves over 12-24 hours. There are several glucometers that can be used at home for this purpose. Insulin must be stored and reconstituted carefully to ensure dosing is accurate. Giving subcutaneous injections of insulin can seem daunting at first, but by following the directions in this handout, it will quickly become second nature to both you and your pet. Hypoglycemia can result from too much insulin, not enough food, or excess exercise. Pet owners are trained to recognized hypoglycemia and treat or obtain emergency veterinary attention.
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Diabetes is an inability of the body to regulate blood sugar caused by an abnormality of the pancreas. It is the second-most common endocrine disease in cats. It causes increased thirst, urination, appetite, and weight loss. Cats most commonly have type 2 diabetes, caused by decreased insulin production or insulin resistance, and it is often associated with obesity. Diabetes is diagnosed by measuring increased levels of glucose in the urine and blood. Diabetes treatment includes insulin injections and dietary changes. Changes in blood sugar must be monitored regularly.